Order Toradol (ketorolac) online in the USA from a licensed pharmacy

| Product Name | Toradol (Toradol) |
| Dosage | 10 mg oral tablets; IM/IV injection strengths vary by presentation |
| Active Ingredient | Ketorolac tromethamine |
| Form | Oral Tablets (10 mg), Injectable (IM/IV), Nasal Spray (brand-specific) |
| Description | Prescription NSAID for short-term management of moderate to severe acute pain in adults; total duration across all routes must not exceed 5 days. |
| Prescription Requirement | Valid prescription required in the USA |
Toradol, known generically as ketorolac tromethamine, is a prescription-only nonsteroidal anti-inflammatory drug (NSAID) in the United States. It is widely used for short-term relief of moderate to severe acute pain in adults, including post-surgical pain, pain after injuries, and acute dental or musculoskeletal pain when opioid-level analgesia might otherwise be considered. In the U.S., ketorolac is available as 10 mg oral tablets as well as injectable IM/IV formulations and a nasal spray option. Due to the potential for serious adverse events, the total duration of therapy across all dosage forms must not exceed 5 days.
As an analgesic, Toradol provides robust pain relief by reducing the production of prostaglandins—chemical mediators responsible for inflammation and pain sensitization—through nonselective inhibition of cyclooxygenase (COX-1 and COX-2). Although effective, ketorolac carries important U.S. boxed warnings related to gastrointestinal bleeding, cardiovascular thrombotic events, renal impairment, and perioperative use around coronary artery bypass graft (CABG) surgery. Because of these risks, Toradol is not intended for minor or chronic pain, and it cannot be used for longer than 5 days in adults.
Toradol (ketorolac) price in the USA
Pricing for Toradol varies by dosage form, quantity, pharmacy, and whether you use insurance or discount programs. In general, generic ketorolac tablets (10 mg) are significantly less expensive than brand-name products. Many U.S. pharmacies offer competitive cash pricing and coupon-based discounts. IM/IV hospital-administered doses are typically billed differently, and nasal formulations may be priced higher than tablets due to proprietary delivery systems.
If your clinician starts treatment with injectable ketorolac for immediate analgesia and then transitions you to 10 mg oral tablets, your out-of-pocket cost will depend on your plan coverage. Patients without insurance frequently find that generic tablets offer the best value for short courses (e.g., 10 to 20 tablets). Because treatment is limited to a total of 5 days, even a small quantity may be sufficient for the complete therapy period.
Retail prices fluctuate regionally across the United States. To get the best deal, compare pharmacy pricing, check discount cards, and ask your prescriber whether a generic option is appropriate for your situation. Our partner network helps streamline fulfillment, price transparency, and fast delivery once your prescription is verified.
Important: Toradol is not an over-the-counter pain reliever in the U.S. You must have a valid prescription, and therapy duration is strictly limited.
Where can I buy Toradol in the USA?
In the United States, Toradol can be dispensed only with a valid prescription from a licensed healthcare professional. You can have your prescriber send the prescription directly to our partner pharmacy or, when available, use affiliated telehealth services to complete a medical consultation and e-prescription. After verification, your medication can be shipped discreetly to your U.S. address.
Our online pharmacy partners are experienced in handling time-sensitive analgesics. With decades of combined industry expertise, they serve patients nationwide, offering secure checkout, transparent pricing, and professional pharmacist support. Whether you’re recovering from surgery or coping with an acute injury, we work to minimize delays so you can start treatment promptly and safely.
Prefer to avoid extra trips to a storefront pharmacy? Ordering online is convenient and efficient. We follow strict U.S. regulations for prescription validation and ensure that every order is processed by licensed pharmacists. You’ll receive step-by-step updates from approval through shipment, along with access to counseling if you have any questions about your medication.
Toradol in the United States
To obtain Toradol legally in the U.S., you will need a prescription. The process is straightforward: request an evaluation from your physician, surgeon, dentist, or telehealth provider, confirm that ketorolac is appropriate for your case, and have the prescription transmitted to our partner pharmacy. Then, choose your preferred dosage form as directed by your clinician—often starting parenterally for immediate effect and transitioning to 10 mg tablets as pain becomes manageable.
What is ketorolac (Toradol)?
Ketorolac tromethamine (brand Toradol) is a potent NSAID designed for short-term treatment of moderate to severe acute pain that would otherwise likely need opioid therapy. By blocking cyclooxygenase enzymes (COX-1 and COX-2), Toradol reduces prostaglandin synthesis, resulting in analgesic, anti-inflammatory, and antipyretic effects. Onset of relief occurs quickly—often within 30 to 60 minutes after an oral dose, and even faster after IM/IV administration—with analgesia typically lasting 4 to 6 hours.
Because NSAIDs can compromise gastrointestinal mucosal protection and renal blood flow, Toradol comes with strict limitations in the U.S.: an adult treatment course must not exceed 5 days in total, regardless of formulation. It is not approved for chronic pain conditions, and it should not be used in pediatric patients for routine pain treatment. Your clinician will determine whether ketorolac is appropriate based on your medical history, concurrent medicines, and the nature of your acute pain.
Compared with many other NSAIDs, ketorolac is recognized for strong analgesia, which is why it is frequently used perioperatively or after significant injuries. However, that potency also comes with a higher risk of serious adverse reactions if misused. Careful screening, the lowest effective dose, and the shortest possible duration are essential.
How Toradol works
Toradol exerts its pain-relieving effect by nonselectively inhibiting COX-1 and COX-2 enzymes, leading to a decrease in prostaglandins that sensitize nerve endings and amplify pain and inflammation. Less prostaglandin activity translates to lower inflammatory signaling, reduced vascular permeability, and less swelling and hyperalgesia at sites of injury or surgical trauma.
Unlike opioids, Toradol does not act on opioid receptors and does not cause euphoria or dependence typical of opioid analgesics. Nevertheless, it still requires close monitoring because NSAID-related gastrointestinal bleeding, renal impairment, and cardiovascular complications can occur, especially in older adults or those with risk factors.
Pharmacokinetics: oral ketorolac is rapidly absorbed, reaching peak plasma levels within approximately 30 to 60 minutes. It is highly protein bound and undergoes hepatic metabolism with urinary excretion of metabolites and a fraction of unchanged drug. Renal function significantly influences ketorolac clearance, which is why dose reductions are required in patients with impaired kidney function and in older adults.
When Toradol is used (indications)
In the United States, Toradol is indicated for the short-term management of moderately severe acute pain in adults that typically requires analgesia at the opioid level. Common clinical scenarios include immediate postoperative pain, acute musculoskeletal injuries, severe dental or oral surgery pain, and certain emergency department presentations where a strong non-opioid analgesic is preferred.
Because Toradol increases bleeding risk and can compromise gastric mucosa, it is generally avoided when hemostasis is critical, in active peptic ulcer disease, or when a patient has a history of gastrointestinal bleeding or perforation. It is also contraindicated in the perioperative setting of coronary artery bypass graft (CABG) surgery and in late pregnancy or during labor and delivery.
Ketorolac is not appropriate for long-term conditions such as chronic back pain or osteoarthritis maintenance therapy. If ongoing pain management is needed after the 5‑day limit, your clinician will switch you to a different treatment plan.
Boxed warnings and key limitations
In the U.S., Toradol carries multiple boxed warnings that reflect its risk profile:
- Gastrointestinal risk: increased risk of peptic ulcers, GI bleeding, and perforation, which can be fatal and may occur without warning symptoms.
- Cardiovascular risk: NSAIDs may raise the risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke. Risk may increase with duration of use; patients with cardiovascular disease or risk factors may be at greater risk.
- Renal risk: ketorolac can cause renal toxicity, particularly in dehydrated patients or those with preexisting renal impairment. Avoid use in advanced renal disease or in patients at risk for renal failure due to volume depletion.
- Bleeding: inhibits platelet function and is contraindicated in patients with active bleeding, high bleeding risk, or incomplete hemostasis.
- Perioperative CABG: contraindicated for the treatment of perioperative pain in the setting of CABG surgery.
- Obstetric use: contraindicated in labor and delivery due to potential adverse effects on the fetus and increased bleeding risk for mother and child.
- Duration limit: maximum combined duration of therapy (all routes) is 5 days in adults.
Dosing and administration
Your clinician will tailor your dose and route of administration based on the severity of pain, clinical setting, and your individual risk factors. The lowest effective dose for the shortest duration is recommended.
Typical adult oral dosing after initial IM/IV therapy: 10 mg by mouth every 4 to 6 hours as needed, not to exceed 40 mg/day. Begin oral therapy only when you no longer require injectable dosing. Do not exceed a total of 5 days of therapy across all routes.
Injectable dosing varies by clinical scenario. In general, single-dose or multiple-dose IM/IV regimens are used in adults, with lower maximum daily doses recommended for older adults (≥65 years), patients weighing less than 50 kg (110 lb), or those with renal impairment. Because parenteral dosing can rapidly alleviate pain, clinicians frequently initiate therapy with IM/IV ketorolac and then transition to oral tablets as symptoms improve.
Renal impairment and older adults
For patients with reduced kidney function or for adults aged 65 and older, lower doses and lower daily maximums are required to limit adverse effects. Your prescriber will assess creatinine, volume status, and concomitant nephrotoxic drugs before and during therapy. If kidney function worsens or you develop signs of renal injury (e.g., reduced urine output, swelling, or unexpected weight gain), contact your healthcare professional immediately.
Transitioning from injection to tablets
A common approach is to administer one or more parenteral doses in the clinical setting to rapidly control pain, then convert to 10 mg oral tablets at home. Once oral therapy begins, take tablets at the lowest effective frequency (typically every 4–6 hours) while respecting the 40 mg/day maximum and the overall 5‑day treatment limit. Do not take other NSAIDs (such as ibuprofen, naproxen, diclofenac, or aspirin at analgesic doses) while using Toradol unless specifically instructed by your prescriber.
Contraindications
Do not use Toradol if any of the following apply to you:
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
- Active peptic ulcer disease, recent GI bleeding or perforation, or a history of recurrent peptic ulcer/GI bleeding.
- Advanced renal disease or patients at risk for renal failure due to volume depletion.
- Labor and delivery, or late pregnancy (risk of fetal renal dysfunction and premature closure of the ductus arteriosus).
- Use for perioperative pain in the setting of CABG surgery.
- Concurrent use with other NSAIDs or aspirin at analgesic/anti-inflammatory doses.
- Known hypersensitivity to ketorolac or any component of the formulation.
Use during pregnancy and breastfeeding
In pregnancy, NSAIDs including Toradol should generally be avoided, especially at 20 weeks or later due to the risk of fetal renal dysfunction and oligohydramnios; near term, NSAIDs can lead to premature closure of the ductus arteriosus. During labor and delivery, ketorolac is contraindicated because of bleeding risks. If you are pregnant, planning to become pregnant, or breastfeeding, speak with your healthcare provider about safer alternatives. Limited amounts of NSAIDs may pass into breast milk; risk–benefit must be evaluated by a clinician before use postpartum.
Pediatric use
Toradol is not approved for routine use in pediatric patients in the United States. Dosing and safety parameters differ substantially from adults; specialized settings may use parenteral ketorolac under strict medical supervision for select cases, but this is not standard outpatient practice. Always follow the guidance of a pediatric specialist.
How to take Toradol safely
If you are prescribed 10 mg oral tablets, take Toradol exactly as directed by your clinician. Taking it with food or milk and a full glass of water may reduce stomach upset. Do not lie down for at least 10 minutes after dosing. Avoid alcohol while using Toradol because it increases the risk of gastrointestinal irritation and bleeding.
Never combine Toradol with other NSAIDs unless your prescriber explicitly authorizes it. Many cold/flu remedies and headache products contain NSAIDs—always check labels or ask a pharmacist. If you miss a dose and still need pain relief, take it when remembered, but do not double up.
Because Toradol can cause dizziness or drowsiness in some patients, use caution when driving or operating machinery until you know how it affects you. If your pain persists beyond 5 days, contact your clinician to reassess the treatment plan.
Pharmacist’s tips for Toradol
Use the lowest effective dose for the shortest possible time. Report any signs of stomach bleeding (black or tarry stools, coffee-ground vomit, or severe abdominal pain) immediately. Stay well hydrated, especially if you are older or have conditions that can affect kidney function. If you are taking blood thinners, antiplatelet drugs, SSRIs/SNRIs, diuretics, ACE inhibitors/ARBs, lithium, or methotrexate, inform your prescriber and pharmacist due to interaction risks.
Keep track of the total duration of therapy. The combined number of days you receive injections and tablets must not exceed five. If you need continued therapy after that, your clinician will switch you to another option.
For dental or surgical pain, your care team may pair Toradol with non-NSAID medications (such as acetaminophen) to enhance pain control while minimizing NSAID exposure. Do not add any medicine on your own without professional guidance.
Safety precautions
Do not use Toradol if you have a history of NSAID-induced asthma or severe hypersensitivity. Avoid taking it with other NSAIDs, including over-the-counter pain relievers, unless specifically instructed. Limit or avoid alcohol. Patients with a history of ulcers, GI bleeding, inflammatory bowel disease, heart disease, hypertension, or kidney problems should discuss risks and alternatives with their clinician before using Toradol.
Older adults are more susceptible to gastrointestinal and renal adverse effects; careful monitoring and lower doses are recommended. Stop Toradol and seek medical care if you develop chest pain, shortness of breath, weakness on one side, slurred speech, severe stomach pain, vomiting blood, black stools, unusual swelling, sudden weight gain, or decreased urination.
Because Toradol can inhibit platelet aggregation and prolong bleeding time, it should be used cautiously in patients with bleeding disorders or those on anticoagulants and antiplatelet agents. Your clinician may order labs or adjust therapy as needed.
Possible side effects
Like all medications, Toradol can cause side effects. Many are mild and temporary, but some are serious and require urgent attention.
Common effects can include: stomach discomfort, heartburn, nausea, vomiting, diarrhea or constipation, gas, dizziness, drowsiness, headache, edema (swelling), or increased blood pressure. Taking Toradol with food may alleviate some gastrointestinal symptoms.
Serious effects may include: gastrointestinal ulceration or bleeding (which can occur without warning), kidney problems (reduced urination, swelling), liver enzyme elevations, severe skin reactions, hypersensitivity reactions (including anaphylaxis), bronchospasm, fluid retention or heart failure exacerbation, and cardiovascular events such as heart attack or stroke.
Symptoms and warning signs
Seek immediate medical help if you notice any of the following warning signs while taking Toradol:
- Black, tarry stools; bright red blood in stools; or vomiting blood/coffee-ground material.
- Severe abdominal pain, persistent heartburn, or unexplained indigestion.
- Sudden chest pain, shortness of breath, weakness on one side, or trouble speaking.
- Swelling of the face, lips, tongue, or throat; difficulty breathing; hives or widespread rash.
- Unusual fatigue, yellowing of the skin or eyes (jaundice), dark urine, or severe nausea/vomiting.
- Rapid weight gain, swelling in the legs or feet, or markedly decreased urination.
If you experience dizziness or drowsiness, avoid driving or operating machinery. Always follow your prescriber’s instructions and do not exceed the recommended dose or duration.
Reporting side effects
If you believe you are experiencing a side effect from Toradol, contact your healthcare provider or pharmacist promptly. You can also report adverse events to the FDA MedWatch program at 1‑800‑FDA‑1088 or via www.fda.gov/medwatch.
Interaction of Toradol with other medicines
Tell your prescriber and pharmacist about all medications, supplements, and herbal products you use. Certain combinations raise the risk of serious side effects or alter how your medicines work. Your healthcare professional may adjust doses, recommend alternatives, or monitor you more closely.
Medications and substances of particular concern include:
- Other NSAIDs or aspirin at analgesic/anti-inflammatory doses (additive GI/renal risk).
- Anticoagulants and antiplatelet agents (e.g., warfarin, DOACs, heparin, clopidogrel) – increased bleeding risk.
- SSRIs/SNRIs (e.g., sertraline, fluoxetine, venlafaxine) – potential increased bleeding risk.
- ACE inhibitors/ARBs and diuretics – heightened risk of renal impairment and reduced antihypertensive efficacy.
- Lithium – NSAIDs may increase lithium levels; monitor for toxicity.
- Methotrexate – NSAIDs can increase methotrexate toxicity; avoid or monitor closely.
- Probenecid – contraindicated with Toradol (increased ketorolac levels).
- Pentoxifylline – generally avoid due to bleeding risk.
This list is not exhaustive. Keep an up-to-date medication list and share it with every healthcare professional involved in your care.
Recommendations from our specialists
For acute pain that genuinely requires strong non-opioid analgesia, Toradol can be a valuable short-term option when used exactly as prescribed. Plan ahead following surgeries or dental procedures by confirming where your prescription will be filled and how it will be delivered. Because total use is limited to 5 days, our team recommends discussing a step-down plan with your prescriber—such as transitioning to acetaminophen or other safer alternatives—once the most severe pain subsides.
Our partner pharmacy network serves patients across the United States with quick prescription verification, pharmacist counseling, and reliable delivery. If Toradol is not appropriate for you based on your medical history, our pharmacists can coordinate with your prescriber to recommend alternatives that fit your needs and risk profile.
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